diff --git a/src/openrct2-cli/CMakeLists.txt b/src/openrct2-cli/CMakeLists.txt
index 6641903752..53c4677d57 100644
--- a/src/openrct2-cli/CMakeLists.txt
+++ b/src/openrct2-cli/CMakeLists.txt
@@ -17,7 +17,7 @@ file(GLOB_RECURSE OPENRCT2_CLI_SOURCES
 add_executable(${PROJECT_NAME} ${OPENRCT2_CLI_SOURCES})
 target_include_directories(${PROJECT_NAME} PRIVATE "${CMAKE_CURRENT_LIST_DIR}/..")
 ipo_set_target_properties(${PROJECT_NAME})
-if (CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (EMSCRIPTEN)
     target_link_libraries(${PROJECT_NAME} ${ICU_DT_LIBRARY_RELEASE} ${ICU_DATA_LIBRARIES})
 endif ()
 target_link_libraries(${PROJECT_NAME} libopenrct2 Threads::Threads)
diff --git a/src/openrct2-ui/CMakeLists.txt b/src/openrct2-ui/CMakeLists.txt
index dc94b9dcab..93b498abbb 100644
--- a/src/openrct2-ui/CMakeLists.txt
+++ b/src/openrct2-ui/CMakeLists.txt
@@ -11,7 +11,7 @@ option(DISABLE_VORBIS   "Disable OGG/VORBIS support.")
 option(DISABLE_OPENGL   "Disable OpenGL support.")
 
 # Third party libraries
-if (CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (EMSCRIPTEN)
     set(USE_FLAGS "${EMSCRIPTEN_FLAGS}")
     if (NOT DISABLE_VORBIS)
         set(USE_FLAGS "${USE_FLAGS} -s USE_VORBIS=1 -s USE_OGG=1")
@@ -42,7 +42,7 @@ else ()
     endif ()
 endif ()
 
-if (NOT DISABLE_OPENGL AND NOT CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (NOT DISABLE_OPENGL AND NOT EMSCRIPTEN)
     # GL doesn't work nicely with macOS, while find_package doesn't work with multiarch on Ubuntu.
     if (APPLE)
         find_package(OpenGL REQUIRED)
@@ -70,7 +70,7 @@ SET_CHECK_CXX_FLAGS(${PROJECT_NAME})
 ipo_set_target_properties(${PROJECT_NAME})
 
 # mingw builds cannot use the PkgConfig imported targets
-if (CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (EMSCRIPTEN)
     target_link_libraries(${PROJECT_NAME} "libopenrct2"
                                     ${SPEEXDSP_LIBRARIES}
                                     ${ICU_DATA_LIBRARIES}
@@ -95,7 +95,7 @@ if (NOT DISABLE_FLAC)
 endif ()
 
 if (NOT DISABLE_VORBIS)
-    if (NOT MSVC AND NOT WIN32 AND NOT CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+    if (NOT MSVC AND NOT WIN32 AND NOT EMSCRIPTEN)
         target_link_libraries(${PROJECT_NAME} PkgConfig::OGG PkgConfig::VORBISFILE)
     else ()
         target_link_libraries(${PROJECT_NAME} ${OGG_LDFLAGS} ${VORBISFILE_LDFLAGS})
diff --git a/src/openrct2/CMakeLists.txt b/src/openrct2/CMakeLists.txt
index 99e2901feb..d150ad0f3e 100644
--- a/src/openrct2/CMakeLists.txt
+++ b/src/openrct2/CMakeLists.txt
@@ -114,7 +114,7 @@ if (NOT DISABLE_GOOGLE_BENCHMARK)
 endif ()
 
 # Third party libraries
-if (CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (EMSCRIPTEN)
     target_include_directories(${PROJECT_NAME} SYSTEM PRIVATE ${ICU_INCLUDE_DIR})
     set(USE_FLAGS "${EMSCRIPTEN_FLAGS}")
     if (NOT DISABLE_VORBIS)
@@ -152,7 +152,7 @@ if (STATIC)
                                      ${ZLIB_STATIC_LIBRARIES}
                                      ${LIBZIP_STATIC_LIBRARIES})
 else ()
-    if (NOT MSVC AND NOT CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+    if (NOT MSVC AND NOT EMSCRIPTEN)
         target_link_libraries(${PROJECT_NAME}
                                      PkgConfig::PNG
                                      PkgConfig::ZLIB
@@ -182,11 +182,11 @@ find_package(Threads REQUIRED)
 target_link_libraries(${PROJECT_NAME} Threads::Threads)
 
 # For some reason, these flags break the check for pthreads. Add them after.
-if (CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (EMSCRIPTEN)
     set(CMAKE_EXE_LINKER_FLAGS "${CMAKE_EXE_LINKER_FLAGS} -s EXPORTED_FUNCTIONS=_GetVersion,_main --js-library ${ROOT_DIR}/emscripten/deps.js")
 endif()
 
-if (NOT MINGW AND NOT MSVC AND NOT CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if (NOT MINGW AND NOT MSVC AND NOT EMSCRIPTEN)
     if (APPLE AND NOT MACOS_USE_DEPENDENCIES)
         execute_process(COMMAND brew --prefix icu4c OUTPUT_VARIABLE HOMEBREW_PREFIX_ICU OUTPUT_STRIP_TRAILING_WHITESPACE)
         # Needed for linking with non-broken icu on Apple platforms
@@ -264,7 +264,7 @@ if (NOT OPENRCT2_COMMIT_SHA1_SHORT STREQUAL "HEAD" AND NOT OPENRCT2_COMMIT_SHA1_
         OPENRCT2_COMMIT_SHA1_SHORT="${OPENRCT2_COMMIT_SHA1_SHORT}")
 endif()
 
-if((X86 OR X86_64) AND NOT MSVC AND NOT CMAKE_SYSTEM_NAME MATCHES "Emscripten")
+if((X86 OR X86_64) AND NOT MSVC AND NOT EMSCRIPTEN)
     set_source_files_properties(${CMAKE_CURRENT_LIST_DIR}/drawing/SSE41Drawing.cpp PROPERTIES COMPILE_FLAGS -msse4.1)
     set_source_files_properties(${CMAKE_CURRENT_LIST_DIR}/drawing/AVX2Drawing.cpp PROPERTIES COMPILE_FLAGS -mavx2)
 endif()